Me, nope. I lived in France, Thailand, Taiwan, Hong Kong and very briefly Manila before returning to my home country at the age of 35. It was not easy in terms of cultural reassimilation, but professionally it was fine. I had a fun conversation with the tax office about retrieving my tax number after never having had an adult, full-time job in the UK.
My home country is far less boring (to me) than Asia, though, because of the cultural stuff that you don't find much of in Asia such as live music. I'm-a just going to move around a lot from now on. A few years in Asia, a few years in Europe to get the best of both worlds.