Ehem, we have met before. The old country wiped out 99.9% of its indigenous peoples. While not pasty white, the only dark we get is cafe au lait…after a week at the beach.
And the sun steals your vitamin D!
Yes, the social prejudice is number one, I was being diplomatic, relaying the most common excuses used/lies told. There are doctors peddling these lies…
That wasn’t at all what I said that but enjoy your strawman.
Yeah OP came in hot for sure.
Absolutely untrue. See https://vdmeta.com
There is only one study that didn’t show a benefit. But that one was stupid. You cannot give normal Cholecalciferol to people in ICU and hope they benefit from it.
Vitamin D prevents the cytokine storm - if people are already delivered to hospital - only chance is high dosage calcifediol - because it increases the levels much faster. However giving vitamin D pre exposure or in early stage has much higher success.
What is mixed - is the quality of the studies. But especially the second Spanish Calcifediol study and the pre exposure studies are pretty well done and very telling!
Now it doesn’t end there why Taiwan is lucky. Studies are showing most superspreaders are obese and/or old.
Taiwan has very few obese people compared to Western countries. But yeah - if you are afraid of being infected, stay the fuck clear from obese people! If they are old - even more.
Coincidence or not? Obese and old people have on average much lower Vitamin D levels…
Of the pre Exposure studies - only two have a known dosage. 50.000IU - in one study, it decreased the amount of people infected by 93%, in the other by 70%
Now considering that 50.000IU once dosage is not even high - it’s highly likely that even a rather small Vitamin D supplementation to everyone insufficient - or just having much less deficient people - is easily enough to get R from 2-3 (that should be the real number without any measures - in winter maybe more - in summer usually anyhow around 1 in the northern hemisphere) to around/below 1.
70% less chance to catch Covid after 50.000IU one time dosage - well that’s pretty much exactly what is needed to get R from 3 to 1.
Now the caveat - those studies were very small. But no pharma company gonna spend money on them - because Vitamin D is dirt cheap. And governments only do what the lobbyists tell them. They pour huge amount of money onto expensive vaccines or medications (remdesivir for example, expensive as crazy and didn’t even work at all as studies showed - but they started using it because of the pharma lobby, and burned loads of money for buying it before there was any study).
Now a smart thing to do would be. Forbid anyone with a BMI over 26 to enter Taiwan (yes body fat percentage would be better, but is harder to calculate) - nearly all superspreaders likely were BMI 26 or above (according to a study related to aerosols), Forbid old people and obese people to enter any places where alcohol is served.
Increase taxes on sugar like crazy. Make people take yearly fitness tests, if they don’t reach a good level make them pay heavy penalties…
And yes wear masks on public transport. Does make sense there (doesn’t make sense if you sit for hours in the same room with others with bad ventilation). Stop wearing masks outside except if really crowded (like soccer stadium, some night markets)
50,000 seems high given that supplements are usually like 2,000 to 5,000.
Edit: never mind. Tiubare right. A one time dose of 50k IU is not high in this setting. Read quickly and did not notice the “one time”.
This meta-analysis is itself not peer reviewed and also uses non-peer-reviewed sources. Have the clinical trials that have been published in peerpreviewed journals also been uniformly positive?
yes - it’s an addition of all kind of studies - some of them peer reviewed - others not. This website lists studies for many different medications - and so far Vitamin D is the second most effective after Ivermectin (which has much stronger side effects - Vitamin D if not overdosed has absolutely 0 negative side effects).
But you cannot call something mixed results - the results are very clear. The quality of many studies are a bit dubious - but that’s very understanding knowing it’s very hard to get funding for double blind studies with large amount of participants.
There are NO other quality studies on Vitamin D. But yet some experts cite old studies about other virus and claim Vitamin D would not work. Often those studies used very low dosage Vitamin D.
Why is 50.000 for the full winter/study perios low? because there are enough studies showing you need to take over 1000IU daily to increase Vitamin D by 10ng/ml. Now most people that are Covid-19 positive had values around 10ng/ml. So minium to not be insufficient would be 2000IU daily! But likely more. And the higher your level - the more you need to take for the same absolute increase.
The 400-800IU recommendation for supplementation is absolute bullocks looking at how many people are insufficient/deficient and how many people have too much Vitamin D (likely 20.000 vs 1)
Just to mix things up 
https://jamanetwork.com/journals/jama/fullarticle/2776738
This one did use a high dose for treatment and the results did not seem supportive of routine treatment with vitamin D for hospitalized Covid-19 patients (it excluded patients on mechanical ventilation or in the ICU).
There is an accompanying editorial that notes people should keep an open mind, but that at present data don’t support routine use for hospitalized patients:
The vdmeta site deals mostly with treatment rather than prevention, as far as I can tell from a quick scan. Is there a separate section on prevention?
Prexp - Pre Exposure - Hence Infection. 3 sections. Early Treatment, late treatment, Pre Eposure.
That is the only negative study - but it’s late treatment with Cholecalciferol. Why should it work? It takes 7-14 days to increase your Vitamin D levels, if you want to create a stupid study, do the way the did.
That’s exactly why Calcifediol exists - it increases your OH25D levels way quicker and way more reliable.
And of course - it’s also mentioned on vdmeta and included (they excluded some studies due to very poor study design). This study has been done properly, but you gotta think before you do a study. And it is well known, that people have Cytokine storm pretty shortly after getting to hospital. Especially in Brazil, where people would wait likely much longer (due to cost) before going to hospital.
They only included moderate to severe cases (light usually includes normal hospital bed). I am thinking maybe this was done on purpose - because they knew beforehand the outcome would be Nil and just wanted to prove a way how Vitamin D fails.
OP, you’re either the world’s most clever scientific mind, or some random idiot on the internet!
vitamin D, vitamin C, gargle 2x day (must have Cetylpyridinium chloride 0.05% or more) elderberry, garlic extract.
that’s what I have gotten after reading related stuff over the past one year on this flu-crap
Seriously??? That is low!
Do we know whether the virus was lowering VD levels? Ie., what were their pre-virus levels? Any studies allowing or discounting that possibility?
Nope, that’s the question. Some doctors claim their levels dropped due to infection, some claim that they were likely to be infected due to their low vitamin D.
There were some studies but they worked with too old data, 5-10 years old.
But then children in northern Italy had around 10 Ng/ml as average in winter recent study. Adults likely lower. So no wonder why covid19 ravaged there.a
Not sure what would be the motivation for this.
There is a lot of active research in this area, including vitamin D for prevention and treatment of Covid-19. So “random idiot” is uncalled for. But I don’t think the causative role of vitamin D deficiency or insufficiency in infection or disease outcomes has been firmly established.
Where did this statistic come from? In the US, plenty of people with Covid are not deficient in vitamin D. Some even have levels above 50 ng/mL:
Mostly it is. Vitamin D has been linked to everything under the sun because there are thousands of one off papers that cant be repeated.