It’s a great “diet.” I just read about it here on Wiki and learned this is the name of the “diet” I’ve been on for a while now.
I think the first thing is to not call it a diet because a “diet” in the general sense is a short term “fix.” You have to see it as a way of life, as it will become your regular eating habit. The upside is you put less junk in your trunk and less processed shit is always a good thing.
The down side I can think of right now is if you are human, there will be times when you will crave something. But when you get that craving, reward yourself. What good is adopting a new eating habit if you are miserable?
I don’t know many pescatarians like myself, so it might be difficult for you to give up land meats at first. And even eating seafood only you should be doing it three times a week only. If you can go all vegetarian, even better, but realistically, it’s not viable for many.
A rot of it is just plain old common sense…Should I have the iceberg lettuce salad with two table spoonfuls of thousand island dressing? Or should I have a romaine salad with red peppers and a balsamic vinegar dressing? Well, duh.
However, the macrobiotic diet does encourage intake of fermented soy. Personally, I am anti-soy products and avoid them as much as possible. There is a big correlation between soy and the thyroid system. Google it.
Actually, my version of the macrobiotic diet avoids soy AND seaweed due to the iodine in seaweed.
I don’t agree it’s only treatment for a specific disorder.
Why have pork chops when you can have sea bass? Know what I’m sayin’? 
Good luck on your new regimen.