To our knowledge, this is the first analysis comparing findings in patients with classic myocarditis, MIS-C myocarditis, and COVID-19 vaccine-related myocarditis. Compared to classic myocarditis, patients with MIS-C had a greater likelihood of full recovery of cardiac function with a faster time to recovery, even when they presented with fulminant myocarditis. Those with COVID-19 vaccine-related myocarditis generally had a milder clinical course, with lower likelihood of cardiac dysfunction at presentation and more rapid recovery when present.
